Which of the following is the single most important practice to eliminate cross-contamination?

Hand sanitizing is the single most important practice to eliminate cross-contamination because it directly addresses the removal of pathogens that can transfer from one client or surface to another. When nail technicians perform hand sanitizing before and after each client, they significantly reduce the risk of spreading bacteria, viruses, and other harmful microorganisms. This procedure not only protects the clients but also safeguards the technician's own health.

Using proper hand sanitizers that meet regulatory standards further enhances the effectiveness of this practice, ensuring a higher level of hygiene in the salon environment. It's a fundamental routine that should be consistently implemented to maintain a safe and clean workspace. Although other practices like draping, rinsing hands, and using spatulas can contribute to hygiene, they do not have the same direct impact on preventing cross-contamination as thorough hand sanitizing does.